Blueprints surgery - download pdf or read online

By Seth J Karp; James Morris; Stanley Zaslau

ISBN-10: 1405104996

ISBN-13: 9781405104999

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B. Action potentials (Fig. 1-9) ENa +65 mV +35 mV Action potential Na+ conductance 0 mV –35 mV K+ conductance Resting membrane potential –70 mV EK –85 mV 0 2 4 Time (msec) 1-9: Changes during generation of an action potential. EK, Equilibrium potential for Kþ; ENa, equilibrium potential for Naþ. Cell Physiology 1. , the electrical signals that encode all information in the nervous system) 2. Generation of an action potential in skeletal muscle cells • The membrane potential reaches a threshold value (approximately À55 mV), which is required for activation of fast, voltage-gated sodium channels.

Other active transport systems are present to pump weak organic acids, halides, and extracellular Kþ across the BBB. • Certain parts of the brain are not protected by the BBB: for example, the pineal gland, which secretes melatonin directly into the systemic circulation, and the chemoreceptor trigger zone, stimulation of which promotes vomiting. Neurophysiology 27 Clinical note: In vasogenic edema (typically secondary to a brain tumor), the blood vessels are poorly developed, are leaky, and lack the transport properties of a normal BBB.

III. Neuromuscular Junction A. Structure of the neuromuscular junction (NMJ) 1. , the plasma membrane of the muscle cell, termed the sarcolemma). 2. The NMJ is also called the motor end plate. B. Mechanism of neuromuscular transmission (Table 1-6) 1. An action potential triggers the fusion of ACh storage vesicles and corresponding release of acetylcholine from the presynaptic neuron. 2. ACh then diffuses across the synaptic cleft and binds to nicotinic receptors on the sarcolemma; the time required for this diffusion is termed synaptic delay.

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Blueprints surgery by Seth J Karp; James Morris; Stanley Zaslau

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