Download e-book for iPad: Calcification and Physiology by Geoffrey H. Bourne

By Geoffrey H. Bourne

ISBN-10: 0121192040

ISBN-13: 9780121192044

Show description

Read Online or Download Calcification and Physiology PDF

Best physiology books

Download e-book for iPad: Biology and Anatomy & Physiology Helps: Tissues by Carolyn Miller

The Biology and Anatomy & body structure is helping sequence is designed to supply a evaluate of the targets and vocabulary coated by way of many teachers. This sequence is in note-like layout to complement any pupil research advisor and gives a self try out on the finish of every textual content to aid with fabric evaluate of the subject coated.

New PDF release: Bound Carbohydrates in Nature (Lezioni Lincee)

Sure carbohydrates are a massive and interesting subject in biochemical and melanoma learn. in line with a chain of invited lectures, this e-book specializes in the precise position that sure carbohydrates play in nature and mirror the author's amazing occupation in biochemical study. another issues coated are the houses of membrane glycoproteins, eager about the resistance of cells to medicinal drugs, and the metabolism of sugars and sialic acids, either one of which shape a pivotal function within the author's reviews.

Read e-book online Color Atlas of Physiology PDF

Now in its 6th version, colour Atlas of body structure covers the total topic of human body structure and brilliantly experiences every little thing clinical scholars want to know to go their pre-clinical body structure checks. Sections comprise the nerves and muscle groups, blood, breathing, the cardiovascular method, digestion, and copy.

Gert Holstege, Caroline M. Beers, Hari H. Subramanian's The Central Nervous System Control of Respiration PDF

Respiratory is without doubt one of the most simple motor actions an important for survival of the person. it truly is less than overall keep an eye on of the vital apprehensive method, which adjusts respiration intensity and frequency counting on the situations the person reveals itself. accordingly this quantity not just experiences the elemental keep an eye on platforms of breathing, positioned within the caudal brainstem, but additionally the better mind areas, that fluctuate intensity and frequency of breathing.

Additional resources for Calcification and Physiology

Sample text

The function of the vesicles in muscle contraction, as in calcification, is not altogether clear; some investigators believe that mitochondria, not the vesicles, control the relaxing factor. In pathological calcification of heart muscle in vitamin D-intoxicated rats, Bonucci and Sadun (1973) observed calcium phosphate within mitochondria in undamaged as well as degenerated myocardial cells. The deposits consisted either of needle-shaped or granular aggregates having the histochemical properties and X-ray diffraction pattern of apatite.

When the capacity of the mitochondria to store calcium in the myocardium is overloaded, and when the concentration of calcium in the microfibrils increases, calcification follows. Normally, the calcium deposits are confined to the SR vesicles and the mitochondria are involved to a much lesser extent. Under pathological conditions, calcification is initiated by myofilament-protein binding of calcium. Speer and Urist ( 1965 ) suggest that the increased calcium concentration in myofilament may lead to protein-calcium phosphate ion association for nucleation and growth of apatite crystals.

More important, the period of synthesis of alkaline phosphatase activity was prolonged by E H D P which suggested that the enzyme activity was correlated with the synthesis of large quantities of noncalcifiable matrix rather than with the mechanism of calcification. However, these experiments confirmed observations of Francis et al. (1969) and Fleish et al. (1973) demonstrating that alkaline phosphatase fails to cleave the Ρ—C—Ρ bonds of diphosphonate, a powerful nonphysiological inhibitor of mineralization.

Download PDF sample

Calcification and Physiology by Geoffrey H. Bourne


by Kevin
4.5

Rated 4.71 of 5 – based on 40 votes