Read e-book online Color Atlas of Genetics PDF

By Eberhard Passarge

ISBN-10: 3131003642

ISBN-13: 9783131003645

From stories of prior editions:

A notable fulfillment, concise yet informative. No geneticist or health care professional attracted to genetic illnesses can be with no copy -- American magazine of clinical Genetics

Ever because the foreign Human Genome undertaking completed its awesome target of sequencing and mapping the whole human genomewith far-reaching implications for figuring out the explanations and prognosis of human genetic disordersprogress within the box has been swift. within the fourth version of the bestselling Color Atlas of Genetics, readers gets an entire evaluation of the sector this present day, with an emphasis at the interface among primary rules and functional functions in medication. The publication makes use of the signature Flexibook structure designed for simple visible studying and retention, and is precious for college students, clinicians, and scientists attracted to protecting present during this fast-moving area.

New issues within the totally revised fourth variation of this atlas:

  • Genetic signaling pathways concerned with genetic disorders
  • DNA fix systems
  • Genomic problems and genome-wide organization studies
  • Cancer genomes
  • Ciliopathies, neurocristopathies, and different teams of causally similar disorders
  • Epigenetic adjustments in sure disorders
  • Illustrated define of human evolution

With nearly two hundred lovely colour plates concisely defined on dealing with pages, and together with worthy tables of knowledge, a thesaurus of phrases, key references, and on-line assets, this publication makes each proposal transparent and obtainable. it truly is a superb advent to genetics and simple genomics for college kids of drugs and biology, in addition to an amazing instructing relief and refresher for investigators in any box of medication or science.

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Sample text

Transient hominids. This group comprises a subfamily of Hominidae, Australopithecinae, w ith a possible ancestral role for th e early hom inin species. Bipedal gait w ith concomi­ tan t anatomical changes o f hands and feet, re­ duction of tooth size, and progressive develop­ m ent of the brain are main characteristics of this group. The m em ber of this group discov­ ered first, by Dart in 1924 (“Taung child”) in South Africa, was Australopithecus africanus with an apparent ability to walk upright.

Stahl) Somatic cell genetics (G. Pontecorvo) Ribosomes (Roberts, Dintzis) Cloning of single cells (Sanford, Puck) 20 Chronology 1959 First chromosomal aberrations in man: trisom y 21 (Lejeune, Gautier, Turpin) Turner syndrome, 45,XO (C. E. Ford) Klinefelter syndrome: 47 XXY (Jacobs and Strong) DNA polymerase (A Komberg) Isoenzymes (Vesell, Markert) Pharmacogenetics (Motulsky, Vogel) 1960 Phytohemagglutinin-stimulated lym­ phocyte cultures (Nowell, Moorhead, Hungerford) 1961 The genetic code is read in triplets (Crick, Brenner, Barnett, Watts-Tobin) The genetic code determ ined (Nirenberg, Mathaei, Ochoa) X-chromosome inactivation (M.

Coalescence time of human and Neandertal reference sequences Split of ancestral human and Neandertal populations Earliest known anatomically modem humans Earliest modern humans in Europe Most recent known Neandertal remains Evolutionary lineage of ancestral human and Neandertal populations A. Origins of humans in relation to Neandertals B. Dispersal of modern humans out o f Africa 32 M olecular Basis o f Genetics The Cell and its Components Cells are the smallest organized structural units of living organisms.

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Color Atlas of Genetics by Eberhard Passarge

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