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By National Council on Radiation Protection and Measurements

ISBN-10: 0929600541

ISBN-13: 9780929600543

ISBN-10: 1435629973

ISBN-13: 9781435629974

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Additional info for Deposition, Retention, and Dosimetry of Inhaled Radioactive Substances: Recommendations of the National Council on Radiation Protection & Measurements (N C R P Report)

Example text

1974). There are few measurements of effects of acute or chronic exposure to inhaled irritants on clearance in the P region (Schlesinger, 1990b1, although numerous irritants have been shown to impair the functional properties of alveolar macrophages (Gardner, 1984). , 1989; Katsnelson and Privalova, 1984; Schlesinger, 1990b). In summary, inhaled irritants have variable and, at times, offsetting effects on particle deposition and clearance. The data on the effects of heavy cigarette smoking are convincing enough to recommend that reduced mechanical clearance rates be used for those individuals smoking more than 10 cigarettes per day.

1. 1 - - PRIMARY SUBDIVISIONS OF LUNG VOLUME Divisions of the respiratory tract gas volume. 28 / 3. PHYSIOLOGY OF THE RESPIRATORY TRACT volumes in this Report are given for gas at body temperature (37 OC), standard pressure (760 mm Hg) and saturated with water vapor. 1. Not all of the tidal volume which passes through the mouth or nasal passages, pharynx and larynx reaches the TB airways and the P region. , NOPL and TB airways in which no gas exchange occurs) is the anatomical dead-space volume.

66 However, due to body size differences between children and adults, the contributions of VT and breathing frequency to total ventilation differ. 1). Ventilatory function improves and then deteriorates with increasing age, although the transition between growth and senescence is not well characterized. Various models have been proposed to describe the functional deterioration that occurs after peak ventilatory function is reached between the ages of 20 to 35 y (Buist, 1982). , aging is constant throughout adult life).

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Deposition, Retention, and Dosimetry of Inhaled Radioactive Substances: Recommendations of the National Council on Radiation Protection & Measurements (N C R P Report) by National Council on Radiation Protection and Measurements


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