By Deborah K. Hansen, Barbara D. Abbott
Highlighting most up-to-date advances in genetics and biochemistry, the thoroughly revised Third Edition studies the sector from uncomplicated technology, medical, epidemiological, and regulatory views. Contributions from best opinion leaders within the box assemble advancements in molecular embryology and mobilephone biology as they observe to difficulties in developmental toxicology. It covers checking out of pharmaceutical and environmental brokers and interpretation of developmental toxicology info, highlighting mathematical and statistical ideas, in addition to the consequences of poisonous publicity at the useful improvement of assorted organs.
The dating among maternal and developmental toxicology is tested, as well as present ideas for learning chemical disposition, metabolism, and placental move. shut realization is given to the regulatory elements of checking out and probability evaluate. Pre- and postconceptional medical care and genetic components in scientific developmental toxicology also are discussed.
Key issues include:
- the roles of apoptosis and sign transduction pathways in basic and irregular development
- the function of epigenetic alterations in development
- the function of meals and person susceptibility
- the application of bioinformatics
- global and specific gene expression changes
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Additional info for Developmental Toxicology
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Developmental Toxicology by Deborah K. Hansen, Barbara D. Abbott