By H. A. Wenner, A. M. Behbehani, L. Rosen (auth.)
Reoviruses are ether-resistant icosahedral viruses 60 to seventy five mp in diameter which comprise ribonucleic acid. they've been recovered from guy and reduce animals and are ubiquitous of their geographic distribution. at the moment, the significance of those viruses as a explanation for human or animal affliction remains to be principally unknown. because of having a couple of strange features, reoviruses have attracted the eye of many employees within the rather couple of minutes considering that they have been first well-known. for instance, investigators drawn to the molecular elements of virology were attracted by way of the bizarre double-helical ribonucleic acid of excessive molecular weight which reoviruses own, whereas these drawn to epidemiology were attracted by way of the incidence of it appears exact viruses in either guy and an strangely big variety of decrease animals. This com pilation relies on details on hand to the writer as of October 31, 1966. II. historical past The time period "reqvirus" was once proposed in 1959 (SABIN, 1959) as a gaggle identify for a few viruses then categorised (SABIN, 1956; RAMOS-ALvAREz and SABIN, 1958) as being exact with, or regarding, ECHO style lO virus.
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Additional info for ECHOViruses Reoviruses
The suggestion has been made that Dutoit resembles the B phase of type 6 viruses, whereas other resemble those of the S phase. But conversion of strain Shropshire from the S to B phase has not been reported. g. Pesascek and Shropshire) may be used in plaque reduction tests. , 1960). Intratypic strains of types 30 and 31, like the ECHO 6 viruses, differ from one another in the HA property, and often vary strikingly with respect to neutralization by homotypic. , in preparation). Interactions with Man and Other Mammalian Species 35 VII.
Behbehani: ECHO Viruses gastro-intestinal and/or respiratory systems. Occasionally cerebellar ataxia, peripheral neuropathies, hepato-renal dysfunction, orchitis, pleurodynia or carditis may intervene during infections involving severalserotypes (Table 4). a) Benign Lymphocytic Meningitis WALLGREN (1924) proposed the term benign meningitis to define a nosological clinical entity characterized by fever, headache, nuchal rigidity and lymphocytic pleocytosis. Lethargy, irritability and vomiting are frequently found in young children.
G. heparin). Serologic variations have been encountered also among type 4 ECHO viruses. The prototype (Pesascek) strain isolated by MELNICK (1954) is poorly neutralized by homologous antisera using the tube test. However, as stated earlier, the same Monogr. Virol. Wenner and A. M:. Behbehani: ECHO Viruses ll-ntisera gave a plaque reduction titer of ~1:2000 (Committee on Enteroviruses, 1957) indicating the impotence of the antigen. , 1957). The weak capacity of the type 4 prototype antiserum to neutralize the homotype was not due to dissociation of virus-antibody complex.
ECHOViruses Reoviruses by H. A. Wenner, A. M. Behbehani, L. Rosen (auth.)