By L. Magos (auth.), Ivan Gut M.D., Ph.D., Miroslav Cikrt M.D., Ph.D., Professor Gabriel L. Plaa Ph.D. (eds.)
The booklet you're simply going to learn represents the larger a part of the papers provided on the foreign convention on commercial and En vironmental Xenobiotics, held in Prague, 1980, and a few contributions by way of those that couldn't come. the 1st target of the assembly used to be to fol low the culture arrange via the 1st convention in 1977. back, we in vited biochemists, pharmacologists, and toxicologists from either East and West, who have been concerned about the examine of disposition, biotransforma tion, and toxicity of vital forms of commercial and environmental toxins, to advertise the alternate of principles and reviews on priorities during this zone of the research of human setting. The invited contributions provide a good survey of and seasoned chanced on perception into particular components of toxicology and disposition of metals and natural chemical compounds, and the sequence of papers on particular topics deliver clean details at the biotransformation and mechanisms of poisonous motion of a number of industrially very important solvents tmd monomers of plastics. instead of from the Preface, the reader may still search suggestions from the Index, which essentially indicates the overlapping of this sector of toxicology with the newest leads to biochemistry. We gratefully recognize the certainty, care, and preciSion of the writer that made this publication attainable. The Editors Contents Metals Metabolic elements within the Distribution and part Time of Mercury After publicity to various Mercurials 1. Magos. With 1 determine . . . . . . . . . . . . . . . . . . .. . . . 1 . . . . . Biliary Excretion of Metals M. Cikrt. With nine Figures. . . . . . . . . . . . . . . . . . . .. . . 17 . . . . .
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The ebook you're simply going to learn represents the larger a part of the papers awarded on the foreign convention on business and En vironmental Xenobiotics, held in Prague, 1980, and a few contributions through those that couldn't come. the 1st target of the assembly was once to fol low the culture manage by means of the 1st convention in 1977.
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Extra info for Industrial and Environmental Xenobiotics: Metabolism and Pharmacokinetics of Organic Chemicals and Metals Proceedings of an International Conference held in Prague, Czechoslovakia, 27’30 May 1980
Dose-dependent biliary excretion and the form of cadmium in the bile. J Toxicol Environ Health 2: 945 -954 Cikrt M (1972) Biliary excretion of 203 Hg, 64 Cu, 52 Mn and 21 0 Pb in the rat. Br J Ind Med 29: 74-80 Cikrt M (1973) Enterohepatic circulation of 6 4 Cu, 52 Mn and 203 Hg in rats. Arch Toxikol 31: 5159 Cikrt M (1978) The influence of Unithiol and Spironolactone on the biliary excretion of 203 Hg in rat. Arch ToxicoI39:219-223 Cikrt M unpublished results Cikrt M, Bencko V (1974) Fate of arsenic after parenteral administration to rats, with particular reference to excretion via bile.
01 =I. D1 0 0 9J88 % J 0 ~ 0 2 4 6 8 10 12 14 16 18 20 22 24 26 TIME [hr) 0,01 Fig. 2. Biliary excretion of 120 Ilg 203 Hg2+ per rat administered intravenously over 24 h: percentage of excreted 20 3Hg per milligramme of bile (triangles). Concentration of 203 Hg in the blood in the course of 24 h after intravenous administration of 120 Ilg of 2 03Hg2:t per rat (open circles). The symbols indicate the mean values from 8-12 rats 23 Biliary Excretion of Metals o 6 to '"52 AAA " - A ~ "£1 6 0 ~ 0 0 Fig.
Am J Physiol 228:296-204 McManus JP A, Isselbacher KJ (1970) Effect of fasting versus feeding on the rat small intestine. Gastroenterology 59:214-221 Mead JF, Bennett LR, Decker AB, Schoenberg MD (1951) The absorption of fatty acids in the mouse intestine. J Nutr 43:477-484 Newry H, Sanford PA, Smyth DH (1970) Effects of fasting on intestinal transfer of sugars and amino acids in vitro. J Physiol 208:705-724 Orr JM, Benet LZ (1975) The effect of fasting on the rate of intestinal drug absorption in rats: preliminary studies.
Industrial and Environmental Xenobiotics: Metabolism and Pharmacokinetics of Organic Chemicals and Metals Proceedings of an International Conference held in Prague, Czechoslovakia, 27’30 May 1980 by L. Magos (auth.), Ivan Gut M.D., Ph.D., Miroslav Cikrt M.D., Ph.D., Professor Gabriel L. Plaa Ph.D. (eds.)