M. Khatami 's Inflammation - ChronicDiseases and Cancer - Cell, Molec. PDF

By M. Khatami

ISBN-10: 9535101021

ISBN-13: 9789535101024

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Extra resources for Inflammation - ChronicDiseases and Cancer - Cell, Molec. Biology [etc.,]

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Cytochrome C electron carriers, glutathione-GSSG/GSH, NAD+/NADH and/or vitamin E regeneration pathways) and impair mechanisms of removal of reactive oxygen species (ROS), reactive nitrogen species (RNS), peroxides and byproducts of the citric acid cycle. Furthermore, drug-induced oxidative damage to mitochondrial integrity and function could further impact catabolism of muscle proteins that would induce sarcopenia, and oxidation of adipose tissues, leading to excessive loss of appetite and weight and MOF (Akamizu and Kangawa 2010, Alberts et al, 2011, Blum et al, 2011, Chen et al, 2011, Del Fabbro et al, 2011, Hall et al, 2011, Khatami 2011 a, b, Okamoto 2002, Suzuki et al, 2011, Terrabui et al, 2007, manuscript in preparation).

2010; Robinson, 2009). 2 (Glaros et al. 2009), which orchestrates immune responses. Fatty acids are indispensable to life for all organisms. They serve as a source of metabolic energy providing twice the energy density compared to carbohydrates or proteins. In addition, fatty acids are an integral part of cellular membranes. The heterogeneity of fatty acids in the membrane contributes to membrane fluidity as well as to the physical and chemical properties of various membrane domains (Stillwell & Wassall, 2003; Wassall & Stillwell, 2008).

Most naturally occurring fatty acids have a chain of an even number of carbon atoms. Fatty acids may be saturated or unsaturated depending on the existence of double bonds. , 2007). This means that the adjacent hydrogen atoms are on the same side of the double bond resulting in a rigid binding, which restricts the conformational freedom of the fatty acid. The more cis double bonds a chain has, the less flexible it is. Thus, cis bonds limit the ability of a fatty acid to be closely packed (Stillwell & Wassall, 2003).

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Inflammation - ChronicDiseases and Cancer - Cell, Molec. Biology [etc.,] by M. Khatami


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