Download e-book for iPad: Knobil and Neill's Physiology of Reproduction, Volume 1-2, by Paul Wassarman, Jimmy D. Neill

By Paul Wassarman, Jimmy D. Neill

ISBN-10: 0125154003

ISBN-13: 9780125154000

The third variation, the 1st new one in ten years, contains insurance of molecular degrees of element coming up from the final decade's explosion of knowledge at this point of organismic association. There are five new affiliate Editors and approximately 2/3 of the chapters have new authors. Chapters ready by means of go back authors are broadly revised. a number of new chapters were extra with regards to being pregnant, reflecting the full of life research of this subject over the past decade.The info lined comprises either human and experimental animals; simple principels are sought, and data on the organismic and molecular degrees are offered. *The prime finished paintings at the body structure of reproduction*Edited and authored via the world's major scientists within the field*Is a synthesis of the molecular, mobile, and organismic degrees of organization*Bibliogrpahics of chapters are broad and canopy all of the correct literature

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Additional resources for Knobil and Neill's Physiology of Reproduction, Volume 1-2, Third Edition

Example text

It was suggested that in the equatorial segment the inner acrosomal membrane is associated with an extensive scaffolding network possibly transmembrane in nature (190). Contents of Acrosome The acrosome serves a critical role in the process of fertilization in mammals. Multiple enzymes are present in the acrosome (Table 2), including acid hydrolases commonly found in lysosomes, and other enzymes specific to spermatogenic cells. Although it has been described as a specialized lysosome (255–257), the acrosome also has the characteristics of a regulated secretory vesicle.

It was suggested that SPAG4 is involved in outer dense fiber assembly by (425–430) (431) (432–433) (434–435) (436–437) (438) (439–441) (442) (443) (443,444) (446–447) (448) forming a link between ODF1 and axonemal microtubules (434). The human SPAG4 gene has been cloned as well (435). SPAG5 (sperm associated antigen 5) also interacts with ODF1 via leucine zippers (436). However, ODF2 does not interact with either SPAG4 or SPAG5, indicating that their interactions with ODF1 involve more than leucine zipper binding.

An additional role of the perinuclear theca might be to link together and stabilizes the association of the acrosome, nucleus, and postacrosomal plasma membrane (182,192,194,226). Other potential roles of the postacrosomal sheath are to generate or maintain the distinctive properties of the overlying plasma membrane (227) or bind the plasma membrane to the sperm (228). These are attractive possibilities, but they remain to be tested experimentally. The Acrosome The acrosome is a unique sperm organelle that originates from the Golgi complex and contains enzymes necessary for the sperm to penetrate through the investments of the egg to achieve fertilization.

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Knobil and Neill's Physiology of Reproduction, Volume 1-2, Third Edition by Paul Wassarman, Jimmy D. Neill


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