By Colleen Smith PhD, Allan Marks MD, Michael Lieberman PhD
This best-selling source makes use of a finished but sensible strategy that scholars comprehend. The authors current proof and pathways to stress how the underlying biochemistry is expounded to the body's total physiological services. targeted case stories express scholars the connection among biochemistry and scientific difficulties. the second one variation has been seriously revised with thoroughly up-to-date illustrations whereas keeping the original, patient-oriented process that made the unique so popular.
A new CD-ROM behind the publication positive factors chapter-by-chapter try out questions, specific 3-D representations of enzyme constitution, PowerPoint slides, and genuine sufferer stories.
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Extra info for Marks' Basic Medical Biochemistry
Its heat capacity and heat of vaporization are remarkably high; as liquid water is converted to a gas and evaporates from the H O δ+ δ– H O R´ C R Hydrogen bond H O H δ + N δ – R´ R Fig. 4. Hydrogen bonds between water and polar molecules. R denotes additional atoms. 1. Distribution of ions in body fluids. Cations Naϩ Kϩ Anions ClϪ HCO3Ϫ Inorganic Phosphate ECF* mmol/L ICF 145 4 12 150 105 25 2 5 12 100 *The content of inorganic ions is very similar in plasma and interstitial fluid, the two components of the extracellular fluid.
As fasting continues, gluconeogenesis progressively adds to the glucose produced by glycogenolysis in the liver. Percy Veere had not eaten much on his first day of hospitalization. His fasting blood glucose determined on the morning of his second day of hospitalization was 72 mg/dL (normal, overnight fasting ϭ 80–100 mg/dL). Thus, in spite of his malnutrition and his overnight fast, his blood glucose was being maintained at nearly normal levels through gluconeogenesis using amino acid precursors.
CHAPTER 3 / FASTING 31 Additional tests were made to help evaluate Mr. Veere’s degree of malnutrition and his progress toward recovery. His arm circumference and triceps skinfold were measured, and his mid upper arm muscle circumference was calculated (see Chap. 2, Anthropometric Measurements). His serum transferrin, as well as his serum albumin, were measured. Fasting blood glucose and serum ketone body concentration were determined on blood samples drawn the next day before breakfast. A 24-hour urine specimen was collected to determine ketone body excretion and creatinine excretion for calculation of the creatinine–height index, a measure of protein depletion from skeletal muscle.
Marks' Basic Medical Biochemistry by Colleen Smith PhD, Allan Marks MD, Michael Lieberman PhD