Medicine - Vander's Renal Physiology by Douglas Eaton, John Pooler PDF

By Douglas Eaton, John Pooler

ISBN-10: 0511018002

ISBN-13: 9780511018008

The most sensible evaluation of renal body structure on hand for USMLE Step 1--completely up-to-date with the newest research

A Doody's center identify for 2015!

Written in a transparent, concise, logical variety, thistrusted textual content stories the elemental rules of thestructure, functionality and pathologies of the human kidney which are crucial for an realizing of medical drugs. Combining the most recent learn with a fullyintegrated educating technique, the 8th version of Vander's Renal Physiology positive factors revised sections that specify how the kidneys impact different physique structures and the way they in flip are tormented by those structures. every one bankruptcy is full of the instruments you must really examine key recommendations instead of in basic terms memorize facts.


  • Begins with the fundamentals and works as much as complicated principles
  • Focuses at the good judgment of renal processes
  • Includes the most up-tp-date examine at the molecular and genetic ideas underlying renal physiology
  • Explains the connection among blood strain and renal function
  • Presents the traditional services of the kidney with scientific correlations to sickness states
  • Includes research questions with a solution key on the endof each one chapter
  • Features studying aids similar to movement charts, diagrams, key notion medical examples, boxed statements to stress significant issues, studying targets, and assessment questions with solutions and explanations

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Extra resources for Medicine - Vander's Renal Physiology

Example text

1–5. A substance is filtered into Bowman’s space and excreted in the urine. How many cell plasma membrane barriers must it cross in order to move from the blood to outside the body? 1–6. A substance is freely filtered. Does this mean that it is all filtered? 1–7. If you immunologically labeled cells of the macula densa with label X, and labeled cells of the thick ascending limb with label Y, would you find labels X and Y in the cortex, medulla, or both? 1–8. Given the generalizations about transport events in the medulla (secretion, reabsorption), can you say that blood flow into the medulla is in any way different in volume from blood flow out of the medulla?

STUDY QUESTIONS 1–1. Is the following statement true or false? The difference between superficial and juxtamedullary nephrons is that superficial nephrons have their glomeruli in the cortex whereas the glomeruli of juxtamedullary nephrons are in the medulla. 1–2. What percentage of the blood entering the kidney flows directly into the medulla without passing through the cortex? 1–3. Substance T is present in the urine. Does this prove that it entered the renal tubule by filtration at the glomerulus?

The glomerulus is the site of filtration—about 180 L/day of volume and proportional amounts of solutes that are freely filtered, which is the case for most solutes (large plasma proteins are an exception). The glomerulus is where the greatest mass of excreted substances enter the nephron. The proximal tubule (convoluted and straight portions) reabsorbs about two thirds of the filtered water, sodium, and chloride. The proximal convoluted tubule reabsorbs all of the useful organic molecules that the body wishes to conserve (eg, glucose, amino acids).

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Medicine - Vander's Renal Physiology by Douglas Eaton, John Pooler

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