By Simon P. Fricker (auth.), Simon P. Fricker (eds.)
The discovery of the antitumour task of cisplatin in 1965 and its next advent into medical trials in 1971 was once the catalyst for a tremendous foreign study attempt investigating the potential for steel compounds in melanoma treatment. Cisplatin now occupies a huge position within the armamentarium of the oncologist because of its effectiveness within the remedy of testicular melanoma. A moment iteration analogue, carbo platin, bargains decreased toxicity including healing job, which provides it a spot within the front-line treatment of genitourinary cancers. those and different successes have inspired the quest for novel metal-based medicines for melanoma remedy. learn has proven that steel compounds have power for task not just as cytotoxic antitumour brokers, but additionally in parts comparable to adjuvant remedy, analysis and immunotherapy. the purpose of this e-book is to check and describe the foremost achievements and advancements bobbing up from this overseas examine attempt. The contributing authors come from labora tories all through Europe and the United States and signify the various disci plines attribute of this study, comparable to medical examine, pharmacology, tumour biology and inorganic medicinal chemistry.
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Metal Compounds in Cancer Therapy by Simon P. Fricker (auth.), Simon P. Fricker (eds.)