By A. Sikkel M.D. (auth.), R. H. Gevers M.D., J. H. Ruys M.D. (eds.)
The process heritage isn't one among soft development. sessions of relative quietness are interrupted by means of classes of wars and revolution. This development resembles that of a river which, earlier than flowing into the delta, has to go numerous rapids. a similar holds for the advance of the technology of drugs. In obstetrics a few of these 'revolutions' or 'rapids' include the advent of conservative obstetrical remedy by way of Lucas Johann Boer initially of the 19th century, the invention of the reason for puerperal sepsis by means of Oliver Wendell Holmes and Semmelweiss among 1843 and 1847, the advent of the main of asepsis through Pasteur in 1874, the advent of prenatal care on the finish of the 9 teenth and the start of the 20 th century (Mijnlieff, Treub, De Snoo), the advance of surgical suggestions, the chance to regard surprise by way of bloodtransfusion, and, ultimately, the purchase of latest ability for the powerful treatment of an infection. most of these advancements have ended in a pointy aid of maternal and perinatal mortality. during this connection it has to be mentioned that this kind of aid might by no means were comprehensive with out the beneficial social adjustments due to which scientific and prenatal care can be made universally on hand. lately there was one other progressive strengthen ment in obstetrics. elements were liable for this: the ap plication of easy sciences in obstetrics, and the dissolution of the isolation with recognize to different medical disciplines.
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Extra info for Physiology and Pathology in the Perinatal Period
Continuous registration of the intrauterine pressure with open tip catheter, transcervical intra amniotic, after artif,icial rupture of the membranes. a. E. were determined with the aid of the Astrup apparatus and the Siggaard-Andersen-Engel normogram. The O 2 saturation was determined by the oxygen saturation meter type OSM 1 (Radiometer Kopenbagen). The glucose concentration was determined by the enzymatic bloodsugar estimation method with glucose oxydase and peroxydase (Boehringer Mannheim), modified by Reinouts van Haga.
Patterns, acidosis in the umbilical artery (pH < 7,20), Apgar Score 1 minute after birth, encircling of the cord round the neck and other particulars. The Apgar score was always exactly established by the same doctor. R. pattern without acidosis occurs frequently in the normal group and less frequently in the pathological group. R. pattern without acidosis occurs fairly frequently in the normal group and seldom in the pathological group. R. S. in these groups is not always optimal, and encircling of the cord occurs perhaps a little more frequently.
56. Dawes O. , Jacobson H. , Mott J. , Shelley H. J. , The treatment of asphyxiated, mature foetal lambs and rhesus monkeys with intravenous glucose and sodium carbonate. J. Physiol. Lond. 169, 167-184 (1963). 57. Ranck J. , Jr. and Windle W. , Brain damage in the monkey, Macaca mulatta, by asphyxia neonatorum. Exp. Neurol. 1, 130-154 (1959). 58. Dawes O. , Hibbard E. and Windle W. , The effect of alkali and glucose infusion on permanent brain damage in rhesus monkeys asphyxiated at birth. J. Pediat.
Physiology and Pathology in the Perinatal Period by A. Sikkel M.D. (auth.), R. H. Gevers M.D., J. H. Ruys M.D. (eds.)