By A. Gholamrezanezhad
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Extra resources for Stem Cells in Clinic and Research
However, this method is widely opposed as fetal tissue originates from elective abortion (Rogers & Casper, 2004). , 2011), umbilical cord (UC) (Fan et al. , 2011), respectively. New efficient stem cells sources would have to exhibit a similary potential to that of ESCs and to be highly proliferative or at least easy to harvest in large numbers. Out of these, the preferred ones are the BM-derived stem cells or UC-derived stem cells. There are two main cell types within the BM: mesenchymal, which are highly proliferative and show a propensity for multi-lineage differentiation (Rogers & Casper, 2004) and haematopoietic, also promising as multipotential stem cell (Kakinuma, 2003; Hao, 2003 as cited in Rogers & Casper, 2004).
1993). Cultured cell lines from human teratomas: windows into tumour growth and differentiation and early human development. Eur. Urol. 23, 82-87. Sandhu JS, Petkov PM, & Dabeva MD, et al. (2001). Stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cells. Am J Pathol. 159(4):1323-34. Schatton T, Murphy GF. et al. (2008). Identification of cells initiating human melanomas. Nature 451 (7176): 345–9, 2008. et al. (2004). Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages.
Co-culture experiments showed that UCMSCs did not induce any proliferation of resting immune cells and also suppressed the purified T cells or activated human peripheral blood mononuclear cells. 7. 1 Myocardial infarction In spite of the fact that the treatment of cardiovascular disease and myocardial infarction has benefited over the past 15 years from advances in pharmacologic and intravascular intervention to include placement of drug-eluting stents and interventional revascularization, this condition is till associated with significant morbidity and mortality.
Stem Cells in Clinic and Research by A. Gholamrezanezhad