Michael Khan, Stella Pelengaris's The Molecular Biology of Cancer PDF

By Michael Khan, Stella Pelengaris

ISBN-10: 1405118148

ISBN-13: 9781405118149

This entire textual content offers a close evaluate of the molecular mechanisms underpinning the advance of melanoma and its therapy. Written via a world panel of researchers, experts and practitioners within the box, the textual content discusses all points of melanoma biology from the motives, improvement and prognosis via to the therapy of melanoma.
* Written via a global panel of researchers, experts and practitioners within the box
* Covers either conventional components of research and parts of controversy and rising value, highlighting destiny instructions for study
* beneficial properties up to date insurance of modern experiences and discoveries, in addition to a superior grounding within the key innovations within the box
* every one bankruptcy contains key issues, bankruptcy summaries, textual content bins, and topical references for additional comprehension and evaluate
* Supported by means of a committed web site at www.blackwellpublishing.com/pelengaris
* a great textual content for upper-level classes within the biology of melanoma, for clinical scholars and certified practitioners getting ready for larger assessments, and for researchers and lecturers within the box

Show description

Read or Download The Molecular Biology of Cancer PDF

Similar cancer books

Download e-book for iPad: Breast Cancer Nuclear Medicine in Diagnosis and Therapeutic by Emilio Bombardieri, Gianni Bonadonna, Luca Gianni

There can by no means be sufficient fabric within the public area approximately cancers, and especially breast melanoma. This booklet provides a lot to the literature. It offers common details on breast melanoma administration and considers all new tools of analysis and treatment. It makes a speciality of nuclear drugs modalities via evaluating their effects with different diagnostic and healing ways.

Read e-book online Voices of Lung Cancer: The Healing Companion: Stories for PDF

Supplied by way of the sufferers, their associates, households, and caregivers of these diagnaosed with lung melanoma, those very own stories offer encouraged perception into the methods households and execs take care of either themselves and the sufferer, achieve a deeper realizing of the relationships, and discover ways to come to phrases with the tip of lifestyles.

Read e-book online Control of Growth Factors and Prevention of Cancer PDF

It really is now obvious that numerous fields of research are converging upon one another because the aim of discovering a pragmatic solution to hinder melanoma is pursued. the current monograph represents the efforts of an interdisciplinary ESO job strength that used to be convened to evaluate interactions of peptide development elements and steroid-like molecules within the prevention of melanoma.

Extra resources for The Molecular Biology of Cancer

Example text

Et al. (2005). Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 436(7051): 725–30. , et al. (2005). BRAFE600-associated senescencelike cell cycle arrest of human naevi. Nature, 436(7051): 720–4. , and Evan, G. (2004). Intrinsic tumor suppression. Nature, 432(7015): 307–15. I. (2002). Suppression of MYC-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell, 109(3): 321–34.

Apoptosis and necrosis are not the only forms of cell death described; others include anoikis, endoplasmic reticulum stress. More recently another potential balance against inappropriate replication has been described, namely irreversible exit from the cell cycle (senescence – see Fig. 9). This is described in detail in Chapter 9. Cells are continually receiving and integrating a variety of both positive and negative growth signals. One intriguing result of much research over the last 20 years has been the appreciation that cells seem only too willing to commit suicide.

Many such changes may actively support tumor cell invasion, survival, and growth and this is particularly important in epithelial carcinogenesis (Chapter 12). Interactions between cancer cells and their environment are thus key determinants of tumor progression. In recent years, a considerable interest has developed in “immune privilege” (Chapter 13). Foreign antigens that enter immunologically privileged sites, of which the eye, brain, and testis are examples, can survive for an extended period of time, whereas the same antigens would normally be swiftly eliminated elsewhere.

Download PDF sample

The Molecular Biology of Cancer by Michael Khan, Stella Pelengaris

by Ronald

Rated 4.15 of 5 – based on 47 votes