By Marcelino Cereijido, James M. Anderson
Because the first certain evaluation of the topic, Tight Junctions introduced jointly various views from top investigators to supply a multidisciplinary evaluate of the sphere. considering that its ebook in 1992, there was an explosion of data approximately tight junctions, relatively within the quarter of molecular constitution, cellphone and molecular biology, genetics and body structure. the sphere has complex so quickly and to date that it affects many components of biology and now has sensible implications for pharmacology of drug supply and knowing a variety of ailments changing epithelial permeability.
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Additional resources for Tight Junctions
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1981. Occluding junctions in cultured epithelial monolayers. Am. J. , 140, C96–C102. Chen, Y. , Schneeberger, E. , and Goodenough, D. A. 2000. Restoration of tight junction structure and barrier function by down-regulation of the mitogen activated protein kinase pathway in Ras-transformed Madin–Darby canine kidney cells. Mol. Biol. Cell, 11, 849–862. , and Kendrick-Jones, J. 1988. Cingulin, a new peripheral component of tight junctions. Nature, 333, 272–276. Claude, P. 1978. Morphological factors influencing transepithelial permeability: a model for the resistance of the zonula occludens.
Tight Junctions by Marcelino Cereijido, James M. Anderson