By Professor Cesare De Martino (auth.), Prof. Jonathan Van Blerkom Ph.D., Prof. Pietro M. Motta Ph.D., M.D. (eds.)
In the previous couple of years, the adoption and world wide proliferation of scientific systems for medically assisted perception were linked to the exam and research of spermatozoa, oocytes and early embryos less than a number of in vivo and in vitro stipulations. those analyses have enabled correlations to be made among the habit of gametes, the development of early embryonic improvement and the initiation of a typical being pregnant. jointly, the findings haven't in basic terms tremendously elevated our figuring out of the method of early human improvement, but in addition have supplied new insights into the beginning and motives of reproductive failure in guy. The learn awarded during this quantity describes contemporary effects derived from the learn of ordinary and irregular styles of human spermatogenesis, oogenesis and early embryogenesis. The chapters talk about aberrations in morphodynamic and morphophysiological tactics that experience scientific relevance in human infertility and belief. of the chapters describe, respectively, the fundamental study that permits the cryopreservation of human oocytes and embryos, and the improvement of in vitro structures that let the learn of mobilephone differentiation and interplay in the course of the peri-implantation interval. whilst correct, every one bankruptcy extrapolates findings from in vitro experimentation to the similar state of affairs that's saw in vivo.
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Additional info for Ultrastructure of Human Gametogenesis and Early Embryogenesis
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76. 77. 78. 79. 80. 81. 82. 83. 84. 85. 86. R, Giannotti P, Natali A, Maver A, Chelo E, Vannelli B, Balboni G: Sertoli cell proteins in human seminal plasma. In: Reproductive Medicine. E Steinberger, G Frajese, A Steinberger (eds), New York: Raven Press, p 465-472, 1986. Vihko KK, Suominen no, Parvinen M: Cellular regulation of plasminogen activator secretion during spermatogenesis. Bioi Reprod 31: 383-389, 1984. Galdieri M, Monaco L, Stefanini M: Secretion of androgen binding protein by Sertoli cells is influenced by contact with germ cells.
A pathologic behavior of the Sertoli cell cytoskeleton seems to occur also in man, as suggested by the frequent observation of a large increase of microfilaments Figure 1-13a-f. Human Sertoli cells. A typical Sertoli cell with an irregular nucleus and a tripartite nucleolus (asterisk) contains large lipid droplets (Figure I-13a). The tubule in Figure I-13b features A dark (Ad) and B spermatogonia (B) along with abnormal spermatids (arrows); Sertoli cells are loaded with lipids. Figures I-13c and d show a spermatogonial arrest of spermatogenesis.
Ultrastructure of Human Gametogenesis and Early Embryogenesis by Professor Cesare De Martino (auth.), Prof. Jonathan Van Blerkom Ph.D., Prof. Pietro M. Motta Ph.D., M.D. (eds.)